| 書目名稱 | Innervation of the Mammalian Esophagus | | 編輯 | W.L. Neuhuber | | 視頻video | http://file.papertrans.cn/467/466658/466658.mp4 | | 概述 | Includes supplementary material: | | 叢書名稱 | Advances in Anatomy, Embryology and Cell Biology | | 圖書封面 |  | | 描述 | .Understanding the innervation of the esophagus is a prerequisite for successful treatment of a variety of disorders, e.g., dysphagia, achalasia, gastroesophageal reflux disease (GERD) and non-cardiac chest pain. Although, at first glance, functions of the esophagus are relatively simple, their neuronal control is considerably complex. Vagal motor neurons of the nucleus ambiguus and preganglionic neurons of the dorsal motor nucleus innervate striated and smooth muscle, respectively. Myenteric neurons represent the interface between the dorsal motor nucleus and smooth muscle but are also involved in striated muscle innervation. Intraganglionic laminar endings (IGLEs) represent mechanosensory vagal afferent terminals. They also establish intricate connections with enteric neurons. Afferent information is implemented by the swallowing central pattern generator in the brainstem, which generates and coordinates deglutitive activity in both striated and smooth esophageal muscle and orchestrates esophageal sphincters as well as gastric adaptive relaxation. Disturbed excitation/inhibition balance in the lower esophageal sphincter results in motility disorders, e.g., achalasia and gastroeso | | 出版日期 | Book 2006 | | 關(guān)鍵詞 | enteric coinnervation; esophageal sphincters; extrinsic system; food; intrinsic system; phase; spinal inne | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-540-32948-0 | | isbn_softcover | 978-3-540-29205-0 | | isbn_ebook | 978-3-540-32948-0Series ISSN 0301-5556 Series E-ISSN 2192-7065 | | issn_series | 0301-5556 | | copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE |
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