Titlebook: Innate and Adaptive Immunity in the Tumor Microenvironment; Eitan Yefenof Book 2008 Springer Science+Business Media B.V. 2008 Antigen.Immu

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Local Tumor Growth and Spontaneous Systemic T Cell Responses in Cancer Patients: A Paradox and Puzzich coexist with a growing tumor in the periphery. This phenomenon, known as “concomitant immunity” suggests that the tumor and its microenvironment prevent systemic antitumor immunity to become effective. Strategies of intervention at the tumor microenvironment are being discussed.

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Tumor Cell Resistance to Apoptosis by Infi ltrating Cytotoxic Lymphocytes,ts develop resistance and they no longer respond to the above therapies. Immunotherapy has been considered as an alternative approach to overcome resistance and several antibody-mediated new cell-mediated therapies have been introduced and yielded significant clinical responses. The development of c

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