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Titlebook: Inhibitors of Protein Kinases and Protein Phosphates; Lorenzo A. Pinna,Patricia T.W. Cohen (Professor of Book 2005 Springer-Verlag Berlin

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書目名稱Inhibitors of Protein Kinases and Protein Phosphates
編輯Lorenzo A. Pinna,Patricia T.W. Cohen (Professor of
視頻videohttp://file.papertrans.cn/467/466476/466476.mp4
概述Includes supplementary material:
叢書名稱Handbook of Experimental Pharmacology
圖書封面Titlebook: Inhibitors of Protein Kinases and Protein Phosphates;  Lorenzo A. Pinna,Patricia T.W. Cohen (Professor of Book 2005 Springer-Verlag Berlin
描述.The aims of this volume?are to highlight the tremendous pharmacological potential of protein kinase and protein phosphatase inhibitors, to provide a thorough overview of the most remarkable achievements in the field and to illustrate how beneficial these studies can be for the advancement of both basic knowledge on biological regulation and deregulation and for the clinical treatment of a wide spectrum of diseases. This goal?is attained by contributions of leader investigators in the field, who?address the issue from different angles. .
出版日期Book 2005
關(guān)鍵詞Anticancer drugs; Antidiabetes targets; Calcineurin-Inhibitor; Cell signalling; Glycogen; Immunosuppressa
版次1
doihttps://doi.org/10.1007/b137900
isbn_softcover978-3-642-42206-5
isbn_ebook978-3-540-26670-9Series ISSN 0171-2004 Series E-ISSN 1865-0325
issn_series 0171-2004
copyrightSpringer-Verlag Berlin Heidelberg 2005
The information of publication is updating

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Inhibitors of Protein Kinase CK2: Structural Aspectsver the last 50 years, very little is known about its precise biological function and mode of regulation. The CK2 holoenzyme is composed of two catalytic .- and two regulatory .-subunits and is classified as an acidophilic Ser/Thr kinase. Unique properties of the catalytic α-subunit are its intrinsi
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Aminoglycoside Kinases and Antibiotic Resistanceiotics threatens to render some infections untreatable by existing drugs. As a result, there is considerable interest in understanding the mechanisms of antibiotic resistance and in identifying ways in which antibiotic resistance can be overcome. Aminoglycoside antibiotics are broad-spectrum bacteri
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Serine/Threonine Protein Phosphatase Inhibitors with Antitumor Activityonine protein phosphatases, notably PP2A, PP4, and PP5, may prove useful for the medical management of human cancer. This chapter will review the discovery and development of natural compounds that were originally shown to have marked antitumor activity and subsequently found to act as potent inhibi
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