Titlebook: Information for a Better World: Shaping the Global Future; 17th International C Malte Smits Conference proceedings 2022 The Editor(s) (if a

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Kirsten Schlebbeging DNA damage in molecular and cellular biology. In DNA Damage Detection In Situ, Ex Vivo, and In Vivo: Methods and Protocols, expert researchers explore the latest advances in the area, covering both recent and established techniques to detect and quantify DNA damage at scales ranging from subcel

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Annemaree Lloyd,Alison Hicksn forks. Several breast and ovarian tumor suppressors, including BRCA1 and BARD1, have been implicated in HR since their discovery in the 1990s. However, a holistic understanding of how they participate in HR has been hampered by the immense challenge of expressing and purifying these large and unst

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Sarah Barriage,Hye Jeong Choi,Anne E. Ray,Michael L. Hecht,Kathryn Greene,Shannon D. Glennf these single-stranded DNA gaps has been instrumental to uncover the mechanisms that allow the DNA replication machinery to skip intrinsic replication obstacles or DNA lesions. DNA fiber assays provide an essential tool for detecting perturbations in DNA replication fork dynamics genome-wide at sin

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Viviane Frings-Hessami,Anindita Sarkern. The mutagenicity of DNA methylating agents, such as methyl methane sulfonate (MMS) and 1-methyl-l -nitrosourea (MNU), is widely appreciated, and is useful in creating mutants in bacterial and human cells .. These mutants, and the identification of mutant genes leading to specific measurable biolo