Titlebook: Influence of Tumor Development on the Host; Lance A. Liotta Book 1989 Kluwer Academic Publishers 1989 DNA.Tumor.cancer.cell.metastasis.tum

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Ion Deregulation, Cell Injury and Tumor Promotionation specifically as it relates to tumor promotion. It has become evident in recent years that ion deregulation plays a significant role in cell division and cell death; concurrently, studies have been performed suggesting significant differences in neoplastic versus normal cells and in the effects

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Multiple Primary Neoplasms: Role of Autopsy. Selected Sites, with Emphasis on Japanrs can explain this trend including an increased detection of early cancer as a result of greater awareness of the problem on the part of the physician and more complete pathologic study of the operation and autopsy specimens.

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Mechanisms of Cancer Invasion and Metastasesnt therapeutic techniques. However, half of the patients with a newly diagnosed tumor will already have metastases. Therefore, understanding the mechanisms involved in the process of tumor invasion and metastases is a major challenge in cancer research. The identification of biochemical factors augm

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Extracellular Matrix and Its Enzymatic Degradation in Tumor Invasionells become detached from the primary tumor and begin to migrate into the adjacent tissue in a process presumably guided by chemotactic factors. In most cases the invading cells reach lymphatic or blood vessels from where they can spread throughout the body, extravasate and form metastatic foci (Fig

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DNA Transfection, Genetic Instability, and Metastasistered function, with the ultimate aim of gene identification and molecular cloning, has enhanced our knowledge of a variety of loci, including oncogenes [see (53), (9) for reviews]. This technique is only now beginning to be applied to the complex process of tumor metastasis. In this chapter, I will

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