Titlebook: Inflammation, Aging, and Oxidative Stress; Stephen C. Bondy,Arezoo Campbell Book 2016 Springer International Publishing Switzerland 2016 A

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Tyrosine Kinase Inhibitors and Neurodegenerative Disordersjor increases in its impact. Current therapies mostly control symptoms for only a limited time. They completely fail to alter or slow down the progression of the disease. Neuronal cell death pathway mediated by activated tyrosine kinases leading to neuronal cell death has recently become a very sign

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Reactive Oxygen Species and Protein Oxidation in Neurodegenerative Diseasearticipants of normal biological processes, but that can indeed produce damage at higher concentrations. They may oxidize specific targets in proteins, with definite regulatory consequences, and enzymes that subsequently reduce and restore their targets have been identified. However, increased level

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Anti-Oxidants, the Aging Brain and Age-Related Brain Disorders disorders. As a result, numerous attempts have tried to use antioxidants to alleviate both types of debilitative conditions. While positive effects of a variety of antioxidant treatments have been found in experimental animals and models of human neurodegenerative disorders, carefully controlled hu

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Antioxidants and Redox-Based Therapeutics in Parkinson’s Diseasenergic neurons in the substantia nigra and their axon terminals in the striatum. Although the etiology of PD is not completely understood and is believed to be multifactorial, oxidative stress and mitochondrial dysfunction are widely considered major contributors offering important clues about disea