Titlebook: Inflammasomes: Clinical and Therapeutic Implications; Mario D. Cordero,Elísabet Alcocer-Gómez Book 2018 Springer International Publishing

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高談闊論

Rotator-Cuff

Lung Diseases,nd small animal disease models that implicate excessive inflammasome responses in the pathogenesis of a number of acute and chronic respiratory inflammatory diseases. Understanding of the role of inflammasomes in lung disease is of great therapeutic interest.

LIEN

Traumatic Injury, trauma is still largely unknown. However, in the following chapter, we provide an overview on the best described inflammasomes in the various settings of trauma, introducing the recent findings on the . best described NLRP inflammasomes and underlying cytokines in the inflammatory response to trauma.

有惡臭

Role of Inflammasomes in the Development of Gastrointestinal Diseases, NOD-like receptors (NLRs) which are major components of inflammasomes in the development and exacerbation of many diseases of human systems. In this chapter, we discuss the role of inflammasomes in some of the most prevalent diseases of the gastrointestinal tract and highlight potential targets for treatment.

Preserve

表皮

Inflammasomes in the Kidney,er inflammasomes in some conditions. While, at least in some disease, the mechanistic details of the involvement of the inflammasome remain to be elucidated, therapies focussed on inflammasomes and their products have potential in treating kidney disease in the future.

Humble

Inflammasomes in Bone Diseases, are characteristics of dysregulated inflammasomes, which are key regulators of innate immunity. In this review, we discuss the role of inflammasomes in bone diseases caused by sterile or non-sterile inflammation.

調(diào)情

Inflammasomes in Clinical Practice: A Brief Introduction,eases opens a door to developing new therapeutic perspectives. However, the rapid increase in the knowledge about inflammasomes is associated with their involvement in clinical practice. Two topics open the way to future lines of research: a clinical trial with the new specific inhibitors and the development of diagnostic tools.

VEN

Inflammasome in the Pathogenesis of Pulmonary Diseases,ta and IL-18 from their precursors into the active forms is tightly regulated by inflammasomes. In this chapter, we structurally review current evidence of inflammasome-related components in the pathogenesis of acute and chronic lung diseases, focusing on the “inflammasome-caspase-1-IL-1 beta/IL-18” axis.