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Titlebook: Inducible Gene Expression, Volume 1; Environmental Stress P. A. Baeuerle Book 1995 Birkh?user Boston 1995 DNA.gene expression.genes.Promote

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發(fā)表于 2025-3-21 17:41:49 | 只看該作者 |倒序瀏覽 |閱讀模式
書目名稱Inducible Gene Expression, Volume 1
副標題Environmental Stress
編輯P. A. Baeuerle
視頻videohttp://file.papertrans.cn/464/463864/463864.mp4
叢書名稱Progress in Gene Expression
圖書封面Titlebook: Inducible Gene Expression, Volume 1; Environmental Stress P. A. Baeuerle Book 1995 Birkh?user Boston 1995 DNA.gene expression.genes.Promote
描述Cells have evolved multiple strategies to adapt the composition and quality of their protein equipment to needs imposed by changes in intra- and extracellular conditions. The appearance of pro teins transmit- ting novel functional properties to cells can be controlled at a transcrip- tional, posttranscriptional, translational or posttranslational level. Extensive research over the past 15 years has shown that transcriptional regulation is used as the predominant strategy to control the production of new proteins in response to extracellular stimuli. At the level of gene transcription, the initiation ofmRNA synthesis is used most frequently to govern gene expression. The key elements controlling transcription initiation in eukaryotes are activator proteins (transactivators) that bind in a sequence-specific manner to short DNA sequences in the of genes. The activator binding sites are elements of larger proximity control units, ca lied promoters and enhancers, which bind many distinct proteins. These may synergize or negatively cooperate with the activators. The do novo binding of an activator to DNA or, if already bound to DNA, its functional activation is what ultimately turns on a
出版日期Book 1995
關鍵詞DNA; gene expression; genes; Promoter; stress; transcription; translation
版次1
doihttps://doi.org/10.1007/978-1-4684-6840-3
isbn_softcover978-1-4684-6842-7
isbn_ebook978-1-4684-6840-3
copyrightBirkh?user Boston 1995
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發(fā)表于 2025-3-21 21:47:03 | 只看該作者
Prokaryotic control of transcription: How and why does it differ from eukaryotic control?,sm of chemicals which suddenly appear in the environment have to be rapidly turned on. We have to recall that the inner bacterial membrane does not allow the entry of most organic chemicals. There has to be a permease, a specific pump, present which transports the chemical into the cell.
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The Role and Regulation of the Jun Proteins in Response to Phorbol Ester and UV Light, Mount, 1982; Walker, 1985), mammalian cells actively respond to those agents by activating DNA repair enzymes and initiating a transcriptional induction response known as the UV response (Karin and Herrlich, 1989; Ronai et al, 1990; Holbrook and Fornance, 1991; Herrlich et al, 1992).
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Mechanism of Signal Transduction by the basic Helix-Loop-Helix Dioxin Receptor,oxins have a biological half-life in humans of the order of a decade, and, due to their pronounced biological and chemical stability, they have become widespread environmental contaminants which can be expected to accumulate within the food chain and persist throughout the ecosystem in the future (Safe, 1990; Gallo et al, 1991).
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PPAR: a Key Nuclear Factor in Nutrient / Gene Interactions?,ional association of low affinity cytoplasmic hormone binding proteins and high affinity nuclear hormone receptors. The latter interact with polymorphic response elements linked to target genes and mediate the hormonal response at the transcriptional level.
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Book 1995ents of larger proximity control units, ca lied promoters and enhancers, which bind many distinct proteins. These may synergize or negatively cooperate with the activators. The do novo binding of an activator to DNA or, if already bound to DNA, its functional activation is what ultimately turns on a
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s are elements of larger proximity control units, ca lied promoters and enhancers, which bind many distinct proteins. These may synergize or negatively cooperate with the activators. The do novo binding of an activator to DNA or, if already bound to DNA, its functional activation is what ultimately turns on a978-1-4684-6842-7978-1-4684-6840-3
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