Titlebook: Induced Mutagenesis; Molecular Mechanisms Christopher W. Lawrence (Chairman) Book 1983 Plenum Press, New York 1983 Hamster.Mamma.attention.

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Replication and Mutagenesis of Irradiated Single-Strand Phage DNAir mutagenic effect. . cause subtle modifications of the bases in DNA (or its precursors) and give rise to mutations by mispairing during DNA replication. Direct mutagens do not require cellular DNA repair activity for their mutagenic effect (i.e. act independently of the bacterial . and . genes) an

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The Use of DNA-Repair-Deficient Mutants of Chinese Hamster Ovary Cells in Studying Mutagenesis Mecha that are deficient in DNA repair processes. From more than 150 UV-sensitive strains tested, five complementation classes were identified, and representative mutants were found to be defective at, or before, the incision step of excision repair. A representative mutant, strain UV-5, was compared wit

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Variation in Response to Mutagens Amongst Normal and Repair-Defective Human Cellsatients suffering from cancer-prone genetic diseases. The objective of these experiments was to determine if cancer proneness at the level of the individual is correlated with either hypersensitivity to the lethal effects or hypermutability to the mutagenic effects of DNA damaging agents. The existe