Titlebook: In Vitro Toxicology Systems; Anna Bal-Price,Paul Jennings Book 2014 Springer Science+Business Media New York 2014 Cell culture.Chemical te

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In Vitro Methods for Cardiotoxicity Testing preclinical safety evaluation and forced the International Conference on Harmonization to develop stringent guidelines for preclinical safety evaluation and to include cardiotoxicity testing as a part of repeated dose toxicity studies. Still there is a gap of species variation in preclinical-to-cli

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Renal Cell Cultureluding transport, metabolism, and the effects of external stimuli such as oxygen tension, nutrition, hormones, and xenobiotics. Indeed, cultured renal tubular epithelial cells were one of the first cells utilized for investigating drug-induced injury. In this chapter, we describe the methods used to