Titlebook: Immunotherapy – A Novel Facet of Modern Therapeutics; Sujata P. Sawarkar,Vandana S. Nikam,Shariq Syed Book 2021 Springer Nature Singapore

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the function of a number of proteins encoded by candidate genes is still unknown. To date, over 20 genes have been shown to play a pivotal role in the origin of DCM. This diversity of genetic etiologies in DCM explains why patients sometimes exhibit additional clinical manifestations, including def

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Vritika Kulwal,Sujata Sawarkarcardiac defibrillator, while radiofrequency ablation has been recently reported as a potential new treatment. In 2016, a scoring system for diagnosis and risk stratification was proposed. This included electrocardiographic alterations, clinical findings, genetic basis, and family history.

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Shariq Syedndrial cardiomyopathy is suspected. Since mitochondria, and thus mutant mitochondrial DNA, are randomly distributed during the cell cycle, disease phenotype may vary greatly..Treatment for mitochondrial cardiomyopathies is mainly supportive and comprises a combination of diuretics, beta-blockers, an

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Pratik Ogale,Vandana S. Nikam,Manish Gautam,Sunil Gairola,S. S. Jadhave most prevalent disease gene. The nonisolated forms of LVNC are caused by a range of rare genetic defects. Until now, in half of familial isolated LVNC, the genetic defect remains unknown. Genetic defects in a large number of sarcomere and other cardiomyopathy genes and in genes primarily associate

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Vandana S. Nikamergo periodic cardiac evaluation for the presence of LVH. In about half of all patients, a disease causing mutation can be detected in one of the genes encoding for sarcomeric proteins. Detection of a disease causing mutation allows predictive genetic testing in relatives, and facilitates identifica

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Krishna Baxi,Munira Momin,Sujata Sawarkarnormalities, ventricular arrhythmias with a LBBB morphology, functional and structural alterations of the RV, and fibro-fatty replacement in endomyocardial biopsy. Two-dimensional echocardiography, cineangiography and magnetic resonance are the imaging tools to visualize structural-functional abnorm

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