Titlebook: Immunotherapy for Pediatric Malignancies; Juliet C. Gray,Aurélien Marabelle Book 2018 Springer International Publishing Switzerland 2018 A

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Immune Adjuvants and Cytokine Therapies,re molecules released by different cell types in the extracellular milieu that play essential roles in intercellular communication. Cytokines represent a category of IA, and will be discussed here in detail, as they have already achieved widespread use in pediatric oncology.

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ncies.Addresses key issues, such as immune-related toxicitie.This book provides a comprehensive overview of current immunotherapy strategies, and how these may be applicable to childhood cancers. The first part of the book reviews how the immune system recognizes cancer, and the various escape mecha

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Monoclonal Antibodies Directly Targeting Antigens on Solid Tumours, dramatically increasing over the years. Although approval rates in paediatric indications stay far behind, the clinical utility of Mabs in paediatric oncology is clearly acknowledged and will be discussed in the following chapters with focus on neuroblastoma.

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Book 2018 of the book reviews how the immune system recognizes cancer, and the various escape mechanisms allowing tumour growth. The importance of the tumor microenvironment and the challenges this may present to achieving effective immunotherapy are discussed. Monoclonal antibodies, cellular, cytokine and v

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NK Cell and NKT Cell Immunotherapy, of both the innate and adaptive immune system, and express an invariant T cell receptor (iNKT cells) that recognizes glycolipid antigens in the context of the MHC class-I-like CD1d molecule. iNKT cells are also being utilized for cancer immunotherapy.

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practical guidelines for implementing individual tests acros.The fourth edition of this textbook offers a scientific and practical context within which to understand and conduct clinical assessments of children’s and adolescent’s personality and behavior. The new edition ensures that the content is