Titlebook: Immunosuppressant Analogs in Neuroprotection; Cesario V. Borlongan,Ole Isacson,Paul R. Sanberg Book 2003 Springer Science+Business Media N

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Protective Effect of Cyclosporin A on Glial Activation and White Matter Alterations Induced by Chroner’s disease, a form of vascular dementia. These cerebrovascular WM lesions have been thought to result from chronic cerebral ischemia, and may be responsible for the cognitive impairments .and gait disorders of the elderly . These lesions are characterized pathologically by diffuse axonal loss, dem

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Blockade of Late-Onset Reduction of Muscarinic Acetylcholine Receptors by Immunosuppressants in Foreenomenon is known as “delayed neuronal death” .. However, pyramidal neurons in the CA3 regions usually survive after transient cerebral ischemia. The ischemia-induced pyramidal cell changes in the hippocampal CA 1 regions suggest that synaptic connections between pyramidal cells and their afferent n

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The Role of Immunophilins in Focal Cerebral Ischemiadescribed as a “chronicle of failed projects and unmet expectations” .. More than 100 agents have been examined in clinical trials, but few have shown convincing clinical benefit. Consequently, there is essentially no effective treatment targeting acute or chronic neurodegeneration in the nervous sy

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Immunosuppressants in Traumatic Brain Injuryh 2 million cases, 220, 000 hospitalizations, and 52, 000 deaths from head trauma occurring each year in the United States alone .. Another 80, 000 to 90, 000 persons each year suffer permanent debilitation. The total cost of TBI in the United States, both direct healthcare and indirect personal and

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utomaton. However, much of what we consider to be the story of artificial intelligence encompasses only the last 75?years, when the field of research and practice of artificial intelligence was named as such by the giants in the discipline at the time. This chapter reviews this history, focusing on