Titlebook: Immunoreceptor Tyrosine-based Inhibition Motifs; Marc Da?ron,Eric Vivier Book 1999 The Editor(s) (if applicable) and The Author(s), under

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人工制品

HLA-Specific and Non-HLA-Specific Human NK Receptors,he expression of one or more MHC class I molecules. Presumably, this allows the immune system to detect and kill certain types of tumor or virus-infected cells trying to evade T cell recognition by downregulating one or more class I molecules (Garrido et al. 1995; Ikeda et al. 1997). Based on the ab

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SLING

Inhibitory Role of Murine Ly49 Lectin-like Receptors on Natural Killer Cells,te the activity of other cells, including T cells and macrophages. While the molecular mechanisms involved in NK cell activation are not completely understood, significant progress has been made in the characterization of the inhibition of NK cell-mediated lysis. It has become clear that the interac

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Interactions of LIRs, a Family of Immunoreceptors Expressed in Myeloid and Lymphoid Cells, with Virbeen found in the remote Tiriyo Indian tribe in Brazil, suggesting that CMV has been present in the human population for a long time (.). hCMV infection usually occurs early in life with only mild and subclinical disease, followed by virus latency that can last for the lifetime of immunocompetent in

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Paired Immunoglobulin-like Receptors of Activating and Inhibitory Types, may include proliferation, elaboration of cytokines, and cytotoxicity, are initiated by receptor-ligand interactions. To maintain immune system homeostasis, the responses initiated by activating receptors are normally counterbalanced by signals propagated through ligation of corresponding inhibitor

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gentle

The Mast Cell Function-Associated Antigen, a New Member of the ITIM Family,gen (MAFA). While trying to identify the still elusive Ca. channel responding to the type 1 Fc? receptor (Fc?RI) stimulus, a series of monoclonal antibodies (mAb) were raised to the rat mucosal-type mast cells of the RBL-2H3 line. One of these mAbs, G63, caused a dose-dependent inhibition of the sec