Titlebook: Immunobiology of Proteins and Peptides VI; Human Immunodeficien M. Zouhair Atassi Book 1991 The Editor(s) (if applicable) and The Author(s)

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Advances in Experimental Medicine and Biologyhttp://image.papertrans.cn/i/image/462106.jpg

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Activation of Prodrugs by Antibody-Enzyme Conjugates,lls. Promising results, both . and ., have been obtained in studies involving immunoconjugates such as MAb-toxins (Vitetta et al., 1987; Blakey et al., 1988), MAb-drugs (Pietersz, 1990; Koppel, 1990), and radiolabeled MAbs (Goldenberg, 1990). Based on these findings, many such conjugates are currently being evaluated in the clinic.

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Strategies for Type-Specific Glycoconjugate Vaccines of ,, reliable estimates (US National Institute of Allergy and Infectious Diseases, 1986) the infant mortality by .. approaches to seven million cases annually and the mortality by encapsulated bacteria (.. type B and ..) accounts for about 38% of the total burden by infectious diseases.

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Immunoprophylaxis of Otitis Media, spectrum of the disease, as well as its impact on child health, the etiology and pathogenesis of otitis media, especially as related to middle ear microbial pathogens, and the present status of otitis media vaccine research.

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Structure and Function in Recombinant HIV-1 gp120 and Speculation about the Disulfide Bonding in thy. The major envelope glycoprotein (gp120 in HIV-1) is of particular interest because it mediates the attachment of the virus to susceptible cells via the CD4 molecule., it contains most of the important epitopes for neutralization of the virus by antibodies., it plays an important role in the proce

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HIV-1 Neutralizing Antibody and Approaches to the Envelope Diversity Problem,fficacious vaccine. Principally for safety reasons, defined subunit polypeptides and proteins devoid of genomic material have been considered as alternatives to attenuated and/or killed virus. Much of the effort to develope such a component vaccine against HIV has been directed at the envelope gene

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,Molecular Mechanisms in the Pathogenesis of AIDS-Associated Kaposi’s Sarcoma, 30% of HIV-1 infected individuals with lesions characterized by mixed cellularity, spindle cells proliferation and neoangiogenesis..The establishment of . and . model systems (AIDS-KS cell cultures and nude mouse) have allowed studies toward the understanding of the pathogenesis of KS..The data pre

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