Titlebook: Immune Mechanisms in Renal Disease; Nancy B. Cummings,Alfred F. Michael,Curtis B. Wils Book 1983 Springer-Verlag US 1983 DNA.allergy.antig

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Glomerular Basement Membrane Antigens,smooth linear pattern along the glomerular basement membrane (GBM) (Hammer and Dixon, 1963). Nephrotoxic serum, produced by immunization with isolated GBM, reacts . by fixing not only to GBM, but also to tubular basement membrane and to Bowman’s capsule as noted by indirect immunofluorescence. The s

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Physical Interactions between Macromolecules and the Glomerular Filter,romolecules (Farquhar, 1978; Brenner .., 1978; Rennke and Venkatachalam, 1977a; Rennke .., 1978, Bohrer .., 1978). Using tracer molecules of appropriate size, charge, and shape, it has been shown that glomerular permeability is markedly dependent on all of these molecular parameters. Thus, molecules

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Pathologic and Functional Correlations in the Glomerulopathies,d also could provide a useful tool with which to assess the response of patients to treatment. Although the measurement of protein selectivity (Joachim .., 1964; Cameron and Blandford, 1966) has gained some popularity for such purposes, there are many inherent problems in this method (Pesce .., 1970

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Glomerular Mesangium: Introductory Remarks,ent upon the size of the molecule, electrostatic charge, and the hemodynamic determinants of glomerular filtration. Morphologic studies suggest that the glomerular basement membrane (GBM) and its epithelial coat act as a barrier which is partially dependent on fixed anionic sites as well as on the s

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Deposition and Removal of Glomerular Immune Complexes: Relationships to the Mononuclear Phagocyte S well documented also. The estimate has been made that over 90% of acute glomerulonephritis is caused by immune complexes. The reasons for the variations in the course and prognosis of glomerulonephritis are not known adequately at this time.

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