Titlebook: IgE Antibodies: Generation and Function; Juan J. Lafaille,Maria A. Curotto de Lafaille Book 2015 The Editor(s) (if applicable) and The Aut

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Debrief

Book 2015llergic diseases and immunity to parasites. It highlights the unique mechanisms involved in the regulation of IgE production at both the molecular and cellular level. Furthermore, it discusses in detail novel findings on how the affinity, specificity and cross-reactivity of IgE can fine-tune mast ce

Texture

Book 2015how the properties of IgE-mediated immunity are employed in the development of IgE therapeutic antibodies. All chapters were written by respected experts in their fields and will appeal to scientists and clinicians alike..

defendant

Molecular Mechanisms of IgE Class Switch Recombination,th Cε resulting in CSR to IgE through a series of molecular events involving irreversible remodeling of the IgH locus. Here, we discuss the molecular mechanisms of CSR and the unique features surrounding the generation of IgE-producing B cells.

混合

IgE Immunotherapy Against Cancer,erapeutic approaches have been shown to be effective in both in vitro and in vivo models of cancer, suggesting the potential use of these approaches in humans. Further studies on the anticancer efficacy and safety profile of these IgE-based approaches are warranted in preparation for translation toward clinical application.

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Biology of IgE Production: IgE Cell Differentiation and the Memory of IgE Responses,nal centers. These processes are essential for long-lasting antibody-mediated protection against infections. IgE antibodies are important for defense against parasites and toxins and can also mediate anti-tumor immunity. However, high-affinity IgE is also the main culprit responsible for the manifes

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