Titlebook: Hypertension and Heart Failure; Epidemiology, Mecha Maria Dorobantu,Giuseppe Mancia,Victor Voicu Book 20191st edition Springer Nature Swit

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Hemodynamic Mechanismsn and management of patients at risk for developing symptomatic heart failure (HF). High blood pressure is the major modifiable risk factor for overt HF. In patients with hypertension, the process of myocardial remodeling/dysfunction starts long before the onset of HF symptoms. The long-term increas

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Natriuretic Peptidesascular and fluid homeostasis. They produce their cardiovascular and renal effects through the binding with guanylyl cyclase (GC)-coupled receptors, namely NPR-A and NPR-B. The NPR-C and neutral endopeptidase (NEP) contribute to NPs clearance. NPs levels progressively increase in heart failure (HF),

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Renal Mechanisms and Heart Failureoor outcomes and all-cause mortality in patients with heart failure. The mechanisms by which the onset of acute heart failure or acutely decompensated chronic heart failure leads to worsening renal function are multiple and complex, being different in acute versus chronic heart failure. In opposite

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Role of Central Blood Pressure and Arterial Stiffeningal stiffening and pressure wave reflection and the left ventricle (LV)-arterial system coupling in heart failure (notably with preserved ejection fraction also referred to as diastolic heart failure) as arterial stiffening can result in impaired active ventricular relaxation and passive ventricular

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Pathophysiology of Hypertensive Heart Diseaseing cardiac alterations induced by hemodynamic and non-hemodynamic factors operating in hypertension. The pathogenetic mechanisms responsible of LVH remain incompletely elucidated..Elevated blood pressure (BP) is the main trigger of events leading to LVH development and diastolic/systolic dysfunctio

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Role of Echocardiography. These alterations in the heart function and structure, along with associated conditions, such as ischemic heart disease, lead to the development of heart failure..The main abnormality induced by arterial hypertension is left ventricular (LV) hypertrophy and diastolic dysfunction. The presence of L