Titlebook: Human Immunodeficiency Virus Reverse Transcriptase; Stuart LeGrice,Matthias Gotte Book 2013 Springer Science+Business Media New York 2013

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HIV Reverse Transcriptase Fidelity, Clade Diversity, and Acquisition of Drug Resistance

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Role of RNase H Activity in NRTI/NNRTI Drug Resistance

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Human Immunodeficiency Virus Reverse Transcriptase

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vent transmission of the virus. The relevance of HIV-1 RT as a drug target has simultaneously triggered interest in basic research studies aimed at providing a more detailed understanding of interactions between proteins, nucleic acids, and small molecule ligands in general terms. In light of the ever-growing978-1-4899-9953-5978-1-4614-7291-9

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Structural Analysis of Periodate-Oxidized Heparinoxidized much more rapidly than the major fraction of the GlcA under all reaction conditions. As the pH is lowered from 7 down to 3, the overall rate of the oxidation slows markedly, but the relative rates of GlcA and IdoA oxidation do not change. The slow rate of oxidation of GlcA residues at all p