Titlebook: Hormone Binding and Target Cell Activation in the Testis; Maria L. Dufau,Anthony R. Means Book 1974 Plenum Press, New York 1974 endocrinol

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Computer Analysis of the Binding Reaction between hCG and Gonadotropin Receptors of the Rat Testis,ydig cells of the rat testis (1–3). The binding of hCG to these receptors has been demonstrated to be a saturable process, and the velocity of binding shows marked temperature dependence (3). Analysis of gonadotropin binding data by Scatchard plots previously indicated the presence of a single class

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The Role of Carbohydrate in the Biological Function of Human Chorionic Gonadotropin,an chorionic gonadotropin (4–6), luteinizing hormone (7–9), and follicle stimulating hormone (10, 11) are located on the plasma membranes of the target cells. The binding is characterized by the high degree of affinity and hormonal specificity, which suggests that the binding sites must have highly

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Coupled Events in the Early Biochemical Actions of FSH on the Sertoli Cells of the Testis,hich occur upon the initial interaction of FSH with its testicular target cells. Previous studies have revealed that a single injection of this gonadotropin to immature male rats results in a rapid stimulation of RNA and protein synthesis (1–3). It is well established that FSH is a polypeptide hormo

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The Production of Androgen Binding Protein by Sertoli Cells,se target cell affected by this gonadotrophin was difficult to pinpoint because of the heterogeneity of cells within the germinal epithelium. Secondly, no specific endpoint for the acute effect of FSH was available.

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FSH Binding in Rat Testes During Maturation and Following Hypophysectomy. Cellular Localization of d cellular site of action in the testis have not been clarified (1). Several morphologic and biochemical parameters are known to be affected by FSH. These effects have been more readily demonstrable in testes of immature or hypophysectomized animals compared to intact adults.

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FSH Receptors in Rat Testes: Chemical Properties and Solubilization Studiies,physiologically significant response. We have previously demonstrated the presence luteinizing hormone (LH) specific receptors in Leydig cell homogenates (1, 2) and follicle stimulating hormone (FSH) specific receptors in seminiferous tubule homogenate (3) of mature rat testes. These studies allowed