Titlebook: Hormonal Regulation of the Menstrual Cycle; The Evolution of Con John G. Gruhn,Ralph R. Kazer Book 1989 Springer Science+Business Media New

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Normal Physiologythout placing it in the larger context of the systematic elucidation of hypothalamic control mechanisms which took place in an explosion of work starting in the mid-1950s. Indeed, to attempt to do so would be a disservice to the reader, as this episode in the history of endocrinology is one of the m

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Therapeutic Developmentsding increase in the ability of clinicians to diagnose and successfully treat various gynecologic disorders. In this final section we focus on three particular areas of advancement which have yielded especially significant benefits.

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Technological Breakthroughsw methodology was referred to as radioimmunoassay (RIA). This conceptually simple technique has revolutionized the study of endocrinology during the last quarter-century. Not only is RIA remarkably precise and accurate, but automated techniques permit the measurement of hundreds of samples at a time.

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Therapeutic Developmentsding increase in the ability of clinicians to diagnose and successfully treat various gynecologic disorders. In this final section we focus on three particular areas of advancement which have yielded especially significant benefits.

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Pathophysiology: The Anovulatory WomanChronic anovulation is the common manifestation of disorders that impact on the hypothalamic-pituitary-ovarian axis in women. Abnormal patterns of menstrual bleeding in turn usually reflect the absence of cyclic ovarian function. In this section, four principal types of anovulation are discussed from a historical perspective.

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978-1-4899-3498-7Springer Science+Business Media New York 1989

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