Titlebook: Homocysteine; Related Vitamins and Christina Bolander-Gouaille,Teodoro Bottiglieri Book 2007Latest edition Springer-Verlag Paris 2007 Depre

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Book 2007Latest editionrises the research within the neuropsychiatric field, but also gives an overview of the underlying biochemistry and of diagnostic aspects. About 1,000 references are given. Christina Bolander-Gouaille, a pharmacist, has for over 10 years specialised in writing reviews/monographs on homocysteine and

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book summarises the research within the neuropsychiatric field, but also gives an overview of the underlying biochemistry and of diagnostic aspects. About 1,000 references are given. Christina Bolander-Gouaille, a pharmacist, has for over 10 years specialised in writing reviews/monographs on homocysteine and

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Book 2007Latest edition the subject are now published each year. The research has long mainly focused on the association between homocysteine and cardiovascular disease, but also pregnancy complications/ fetal malformations. There is, however, an increasing interest in the connection between the homocysteine metabolism an

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Introduction,The importance of homocysteine as a risk factor or risk marker is becoming a familiar concept. Since the early 1990s a constantly increasing number of studies have been published on homocysteine. It has also been the topic of four international conferences, in 1995, 1998, 2001 and 2003.

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What is Homocysteine?,Homocysteine was first described by Butz and du Vigneaud in 1932. They obtained the product by treating methionine with concentrated acid. This was the beginning of a most fascinating research story, which Finkelstein recently highlighted in a review (Finkelstein JD, 2000b).

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How can Homocysteine be Neurotoxic?,The proposed pathogenetic mechanisms, by which hyperhomocysteinemia may cause vascular damage, cognitive impairment, psychiatric and neurological complications, congenital defects, and pregnancy complications, converge.