Titlebook: High-Throughput Glycomics and Glycoproteomics; Methods and Protocol Gordan Lauc,Manfred Wuhrer Book 2017 Springer Science+Business Media, L

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Methods in Molecular Biologyhttp://image.papertrans.cn/h/image/426799.jpg

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Ubiquitous Importance of Protein Glycosylation,parts of glycoproteins have essential roles in many key biological processes. This chapter describes the effect of glycosylation on the structure and function of proteins, with emphasis on regulation of protein half-life and modulation of protein function by alternative glycosylation. In addition, t

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Laboratory Experimental Design for a Glycomic Study, important in all scientific studies in order to ensure valid and sometimes definitive conclusions can be made. The design of experiments, also called experimental design, addresses the challenge of structuring and conducting experiments to answer the questions of interest as clearly and efficiently

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The Use of Multiple Reaction Monitoring on QQQ-MS for the Analysis of Protein- and Site-Specific Glns isolated thereof. However, during such analyses the N-glycan are released from the protein backbone and therefore site- and protein-specific information is lost. There exists a need for high-throughput methods that allow quantification of site- and protein-specific glycosylation patterns from com