Titlebook: High Energy Astrophysical Techniques; Rosa Poggiani Textbook 2017 Springer International Publishing Switzerland 2017 Observational astrono

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Rosa Poggianiapeutics focusing in particular on antisense oligonucleotide analogues carrying modifications in the backbone and sugar. Brief mention is made of siRNA development and other applications that have by and large utilized the same modifications. We also point out the pitfalls of the use of nucleic acid

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Rosa Poggianid DNA backbones can cause immune activation which is concentration-and length-dependent and sequence-independent. However, the different backbones currently under development for antisense applications differ greatly in the degree to which they induce immune effects. As might be expected, neutral ba

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reas (hereafter simply referred to as pancreatic cancer) occurs more frequently in African-Americans than in European-Americans. The disease progresses rapidly. Pancreatic cancer is usually refractory to treatment, with a median survival time of 12 mo. Overall, only 1% of patients live more than 5 y

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Rosa Poggianiides are being designed and studied in relation to hypertension, various cancers, inflammatory bowel disease, brain disorders, the blood-brain barrier, and drug delivery.Highlights include RNA-based therapies for many diseases, up-to-date methods and applications, and insight into the enormous poten

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