Titlebook: Herpes Simplex Virus; Adrian Mindel Book 1989 Springer-Verlag Berlin Heidelberg 1989 Herpes simplex.Sexually Transmitted Diseases.cancer.c

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hic Society’s Global Photography Contest. The homemade-looking structure of the cages and the horror of the monkeys’ captivity made up the sad photo.. In 2013, Li Feng, the same Chinese photographer, won another prize for a series of photos about the same subjects — laboratory monkeys and their live

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Epidemiology,atic, which makes epidemiological studies difficult. One of the fundamental biological properties of HSV (and other human viruses of the herpes group — varicella zoster, cytomegalovirus and Epstein-Barr virus) is the ability to establish latency following the initial infection. This ability (discuss

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Pathology and Pathogenesis,ral replication, occurring first in epithelial cells and resulting in ultimate cell death; and (2) a non-productive (or latent) infection, occurring in nerve cells (see Chap. 2). The productive infection causes most of the clinical symptoms and signs associated with herpes, from the most trivial cut

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Laboratory Diagnosis,fection. Other techniques which may be used include the detection of viral particles or viral antigens in infected tissues, histopathological features consistent with HSV on biopsy, and the use of serological tests. The sensitivity of most of these techniques depends on the amount of virus in the sp

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Treatment, Prevention and Control,ns. Prior to the introduction of acyclovir, treatment was limited largely to the use of extremely toxic drugs for the management of severe infections and also symptomatic treatment for the milder manifestations of the various diseases (including labial and genital herpes). In this chapter I review t

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Clinical Features: Locally Defined Sites,nts, the predominant symptoms are fever, listlessness and an unwillingness to eat or drink, whereas older children or young adults complain of a sore throat (Dodd et al. 1938; Sheridan and Herrman 1971; Hale et al. 1963; Young et al. 1976; Buddingh et al. 1953; Evans and Dick 1964).