Titlebook: Hepatocellular Carcinoma; Diagnosis and Treatm Brian I. Carr Book 2016Latest edition Springer International Publishing Switzerland 2016 gas

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MicroRNAs and Hepatocellular Carcinomave noncoding RNA species. One class of such small noncoding RNA is microRNA (miRNA), comprised of a group of well-conserved, small RNA molecules (21-23 nucleotides) that can up- or down-regulate gene expression in normal and abnormal cellular activities by base pairing with 3′ untranslated regions (

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Hepatocellular Carcinoma as a Paradigm for a Systemic Evolutionary Approach to Cancereappearance of its ancestral subsystems, the archaea (genetic material and cytoplasm) and the prokaryote (mitochondria), which operate autonomously or uncoordinatedly. This unpaired coordination can be caused by changes in the eukaryote environment, mainly inflammation, damage to mitochondrial DNA o

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HCC and Its Microenvironmentway influence, in which the growing tumor can damage the liver parenchyma, and the microenvironment can influence the tumor biology. The latter occurs as a result of multiple factors, including immune cells and their cytokines, platelets and their growth and inflammatory factors and endothelial cell