Titlebook: Heparanase; From Basic Research Israel Vlodavsky,Ralph D. Sanderson,Neta Ilan Book 2020 The Editor(s) (if applicable) and The Author(s), u

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CRP743

Heparanase: A Dynamic Promoter of Myeloma Progressionma tumor chemoresistance. Discovery of these multiple tumor-promoting pathways that are driven by heparanase identified the enzyme as an ideal target for therapy, an approach?recently tested in a Phase I trial in myeloma patients.

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Involvement of Heparan Sulfate and Heparanase in Neural Development and Pathogenesis of Brain Tumorsche, interact specifically with a large number of physiologically important molecules and vital roles for HS biosynthesis and degradation in neural stem cell differentiation have been presented. HSPGs are composed of a core protein with attached highly charged, sulfated disaccharide chains. The majo

Peak-Bone-Mass

Heparanase: A Potential Therapeutic Target in Sarcomasesents a potential therapeutic approach in sarcoma. In this chapter, we summarize the current knowledge about the biological significance of heparanase expression and its potential as a therapeutic target in subtypes of both soft tissue and bone sarcomas. Particular emphasis is given to the involvem

endoscopy

Anal-Canal

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污點

expository

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