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Titlebook: Hemoglobin Disorders; Molecular Methods an Ronald L. Nagel Book 2003 Humana Press 2003

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發(fā)表于 2025-3-21 18:31:01 | 只看該作者 |倒序瀏覽 |閱讀模式
書目名稱Hemoglobin Disorders
副標題Molecular Methods an
編輯Ronald L. Nagel
視頻videohttp://file.papertrans.cn/426/425603/425603.mp4
概述Includes supplementary material:
叢書名稱Methods in Molecular Medicine
圖書封面Titlebook: Hemoglobin Disorders; Molecular Methods an Ronald L. Nagel Book 2003 Humana Press 2003
描述Hemoglobin and Hemoglobinologists This volume, Hemoglobin Disorders: Molecular Methods and Protocols, will be introduced with a review of the great milestones in the field, and the scientists responsible for those achievements. The history of hemoglobin can be divided into three periods: the Classical period, the Modern period, and the Post-Modern period. I am inclined to include as the four major members of the classical period Francis Roughton, Quentin Gibson, Jeffries Wyman, and Linus Pauling, not only because of their achievements, but also because of the superb scientists they trained and/or influenced. Francis John Worsely Roughton (1899–1972) (Fig. 1), in his laboratory at Trinity College in Cambridge, England, made the first measurements of the rapid reaction of oxygen with hemoglobin at the millisecond scale, at first by flow-mixing methods and later by flash photolysis. He not only opened an era of molecular research of hemoglobin, but also invented the methodology for fast reactions through the use of laser technology, which was later improved by others so that even faster reactions could be detected. Another contribution of Roughton was the education of Quentin H. Gibso
出版日期Book 2003
版次1
doihttps://doi.org/10.1385/1592593739
isbn_softcover978-1-61737-278-0
isbn_ebook978-1-59259-373-6Series ISSN 1543-1894 Series E-ISSN 1940-6037
issn_series 1543-1894
copyrightHumana Press 2003
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Jean Kister,Henri WajcmanThis series is written for undergraduate medical students as an introduction to the . approach to medicine. The author believes that the adoption of . in place of traditional ones, immediately makes medicine easier to learn, easier to remember, easier to communicate and easier to use.
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John S. Olson,Erin W. Foley,David H. Maillett,Eden V. PasterThis series is written for undergraduate medical students as an introduction to the . approach to medicine. The author believes that the adoption of . in place of traditional ones, immediately makes medicine easier to learn, easier to remember, easier to communicate and easier to use.
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Solubility Measurement of the Sickle Polymer,In sickle hemoglobin (HbS), a valine is substituted for glutamic acid in the sixth codon of the globin chain. This change endows deoxyHbS, but not oxyHbS, with a new property: the capacity to polymerize. This new property reduces the pliability of the red cell, an indispensable property to navigate the microcirculation.
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Hemoglobin Disorders978-1-59259-373-6Series ISSN 1543-1894 Series E-ISSN 1940-6037
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