Titlebook: Hematopathology; Genomic Mechanisms o Domnita Crisan Book 2011 Springer Science+Business Media, LLC 2011 Cytogenetics.Hematologic Malignanc

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ded into two classes: the first class consists of those methods whose approximate equations are also expressible as integral equations with the regions of integration, measures, and kernels perturbed from the corresponding quantities in the original equation. In particular, this class includes quadr

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Molecular Techniques in Hematopathology, Southern blot and hybridization assays to polymerase chain reaction and its variants to gene expression profiling and single-nucleotide polymorphism analysis, and more recently to microarray technology and whole-genome analysis. Despite technological advancements, molecular techniques are criticall

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Update on the Molecular Pathology of Precursor Lymphoid Leukemias, 10–15% and 25% of ALL in children and adults, respectively. Although they may develop at any age, the precursor lymphoid malignancies arise most frequently in children, in whom ALL is the most common malignancy. The lineage of the malignant lymphoblasts, most commonly determined by flow cytometry-b

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Molecular Pathology of Mature B-Cell and T-Cell Lymphomas,argeted therapy for lymphoma. This chapter will focus on the molecular pathogenesis of lymphoma and discuss current clinical molecular diagnostic testing and its limitations and emphasize interpretation of molecular results in the context of clinical features, morphology, or other studies.

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Molecular Pathology of Myeloproliferative Neoplasms,ese insights are now reflected in the way myeloproliferative neoplasms are diagnosed and classified. The 2008 WHO Classification [1] groups the myeloproliferative neoplasms largely according to their associated molecular abnormalities, many of which involve tyrosine kinases (see Table 7.1). CML is d

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2197-7852 l be of great value to hematologists, oncologists, pathologists, internal medicine and pediatric specialists, as well as bioscientific staff and laboratorians in private hospitals and academic institutions. .978-1-61779-708-8978-1-60761-262-9Series ISSN 2197-7852 Series E-ISSN 2197-7860