Titlebook: Handbook of Oxidative Stress in Cancer: Mechanistic Aspects; Sajal Chakraborti,Bimal K Ray,Sushanta Roychowdhur Living reference work 2020

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Impact of , in Cancer Drug Resistance Development,gh subsequent medications become a failure. Several lines of medications are opted to minimize the mortality, but the outcome is not good because of mild-to-severe side effects together with therapy. In general, chemotherapy is a common practice for various cancers due to cost-effective availability

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Scaffold-Based Selective ROS Generation as Viable Therapeutic Strategies Against Cancer,n increasing field of evidence suggests that cancer cells contain an abnormally high content of ROS, and this biochemical attribute can be utilized for selective killing. Diverse chemotherapeutic agents have been developed that attack cancerous cells through several mechanisms, such as by amplifying

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Targeting Oxidative Stress in Cancer,of tumor-bearing state in the different organs as well as treatment strategy to counteract with the carcinogenesis. The oxidative stress arises from exogenous origins, i.e., ultraviolet rays as well as endogenous origins at the cellular level with the involvement of mitochondria. Modifications of th

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Cutaneous Unfolded Protein Response (UPR) and Endoplasmic Reticulum (ER) Stress,tasis (also called proteostasis) is controlled through the organized action of proteostasis networks that can sense and correct the undesirable proteomic changes to restore protein homeostasis. Although the proteostasis network has remarkable adaptability and robustness, proteostasis balance may bre

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Biomarkers of Oxidative Stress and Its Dynamics in Cancer,sses, such as amino acid and fatty acid metabolism, and oxidative phosphorylation. Mitochondria are also an important source of reactive oxygen species (ROS). The biomarkers of oxidative stress could be high demands to balance the ROS productions. However, the abnormal function of antioxidant respon