Titlebook: Handbook of Drug Monitoring Methods; Therapeutics and Dru Amitava Dasgupta Book 2008 Humana Press 2008 Detailed mechanisms.False negative.F

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Introduction to Drugs of Abuse Testing,cussed. The importance of initial test immunospecificity on test accuracy will be examined for the common drug groups. The need for confirmation will be discussed and the basic principles of mass spectrometry including gas chromatography-mass spectrometry, liquid chromatography-mass spectrometry, and tandem mass spectrometry will be presented.

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Book 2008therapeutic drug monitoring and drugs of abuse as well as alcohol testing with relevant theory, mechanism, and in-depth scientific discussion on each topic. This volume is the perfect handbook and quick reference for any clinical laboratory, allowing clinicians to find the potential source of a fals

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,R?umversuche an Stahl 16 Mn Cr 5,munoassays. However, immunoassays are not available for all drugs monitored in clinical laboratories, for example lamotrigine, protease inhibitors, and new generation of anticonvulsants. For analysis of these drugs, GC, HPLC, or HPLC combined with tandem mass spectrometric techniques are used.

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Pitfalls in Measuring Antidepressant Drugs, for screening purpose in case of a suspected overdose. However, immunoassays for TCA also suffer from many limitations including cross-reactivity of active metabolites and are not suitable for therapeutic drug monitoring. Limitations of various assays for estimation of antidepressants and some tips to deal with these limitations are described.