Titlebook: HPV Infection in Head and Neck Cancer; Wojciech Golusiński,C. René Leemans,Andreas Dietz Book 2017 Springer International Publishing Switz

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HPV in Head and Neck Cancer—30?Years of Historytion were the first to propose the HPV involvement in a subgroup of head and neck cancers. Brandsma and Abramson demonstrated HPV16 DNA in tonsillar SCCs in 1989. Since the early 2000s, HPV research of head and neck squamous cell carcinomas (HNSCC) has made impressive progress, confirming that the s

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0080-0015 and nonsurgical treatment as well as vaccination.Describes pThis book is exceptional in presenting an interdisciplinary approach to the subject of human papillomavirus (HPV) infection in the context of head and neck cancer. Leading experts in the field discuss the epidemiology and molecular biology

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https://doi.org/10.1007/978-3-030-33912-8e compared to those with HPV-negative tumors. In fact, as a surrogate of HPV infection for clinical studies, an immunohistochemical expression of p16 protein is used. In the following chapter, the spectrum of squamous cell carcinomas variants with indication of the percentage cases with proved HPV infection will be presented.

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https://doi.org/10.1007/978-3-642-33603-4al behavior, and other related factors such as tonsillectomy performance. This information is essential in order to understand the burden of the disease and its dynamics and changing patterns, as well as for planning and assessment of the potential impact of HPV-based preventive strategies for HNCs.