Titlebook: HLA Typing; Methods and Protocol Sebastian Boegel Book 2024Latest edition The Editor(s) (if applicable) and The Author(s), under exclusive

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https://doi.org/10.1007/978-94-015-0929-9genes are identified, to fully understand the genetic basis of human traits. Different HLA imputation methods have been developed, each with its own advantages, and recent methods have been improved in terms of imputation accuracy and computational costs. Here, I describe Deep*HLA, a recently publis

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https://doi.org/10.1007/978-0-230-59725-9 complex (MHC) region. These methods predict HLA classical alleles using dense SNP genotypes, commonly found on array-based platforms used in genome-wide association studies (GWAS). The analysis of HLA classical alleles can be conducted on current SNP datasets at no additional cost. Here, we describ

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The Cultural Revolution in Productiony cases a transplant cannot be fully matched, due to widespread variation across populations and the hyperpolymorphism of HLA alleles. Mismatches of the HLA molecules in transplanted tissue can be recognized by immune cells of the recipient, leading to immune response and possibly organ rejection. T