Titlebook: HIV and the Brain; New Challenges in th Robert H. Paul,Ned Charlton Sacktor,Karen Tokie Ta Book 2009 The Editor(s) (if applicable) and The

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Homocysteinemia and Hypertension(.–.), which are often attributed to disruptions in frontal-striatal circuitry (., .). These HIV-associated deficits generally worsen with infection staging (.) , and decline in psychomotor speed appears to be the most robust (.,.) . Although dementia occurs in a relatively small number of HIVinfect

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Neurocognitive Changes in AIDS: Evolution of Treatment of HIV Infection,ly in major US cities on the East and West coasts. In most cases, the individuals had no prior indication of immunodeficiency, which provided the basis for nomenclature of AIDS that was applied to this syndrome by the CDC in 1982.

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New Insights into HIV Neuropathogenesis,pathophysiology of neurological complications due to HIV infection was obvious. As in other retroviruses that had been studied prior to HIV, such as visna virus that infects sheep causing an encephalopathy, it was thought that the infection of macrophages would be sufficient to drive all the glial a