Titlebook: HCV: The Journey from Discovery to a Cure; Volume I Michael J. Sofia Book 2019 Springer Nature Switzerland AG 2019 HCV genome.Molecular Vir

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HCV: The Journey from Discovery to a Cure978-3-030-28207-3Series ISSN 1862-2461 Series E-ISSN 1862-247X

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Topics in Medicinal Chemistryhttp://image.papertrans.cn/h/image/420175.jpg

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A Modified Vision of Divine Determination, The history of the discovery and optimization of leads acting at each of these sites is discussed. The many clinical candidates that emerged from these efforts are described, together with their impact on emerging regimens of increasing effectiveness.

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Evolution of HCV NS5B Non-nucleoside Inhibitors The history of the discovery and optimization of leads acting at each of these sites is discussed. The many clinical candidates that emerged from these efforts are described, together with their impact on emerging regimens of increasing effectiveness.

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From B to Non-B to C: The Hepatitis C Virus in Historical Perspectivety. The major breakthrough occurred in the late 1980s when the Chiron Corporation cloned the NANBH agent and renamed it the hepatitis C virus (HCV). Adding HCV serologic testing, and later molecular testing, to routine donor screening virtually eradicated TAH with current risk estimated to be one ca

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HCV Molecular Virology and Animal Modelsnstitute the current anti-HCV regimens with cure rates of above 95%. This chapter is divided into two parts. The first part begins with a short introduction to HCV and its life cycle and reviews insights into biochemical and functional characteristics of HCV RNA elements and proteins. The second par