Titlebook: HCV: The Journey from Discovery to a Cure; Volume II Michael J. Sofia Book 2019 Springer Nature Switzerland AG 2019 NS5B Inhibitors.NS4B In

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Development of ZEPATIER? (HCV) infection. This novel direct-acting antiviral (DAA) regimen combines elbasvir, a selective inhibitor of the HCV nonstructural protein 5A, and grazoprevir, a reversible competitive inhibitor of the HCV nonstructural protein 3/4A protease. After extensive preclinical testing and evaluation of s

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Real-World Evidence and Hepatitis Cions and safety among those with all stages of liver disease, including cirrhosis, have been repeatedly demonstrated in studies encompassing all classes of DAAs. Real-world evidence has confirmed that DAA therapies used in usual clinical practice achieved similar rates of sustained virological respo

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