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ARBOR

Functional Role of Gangliosides in Neuronal Motility,ns is thought to be the underlying cause of several congenital cortical disorders.Thus, an understanding of the dynamics and molecular mechanisms of neuronal cell migration could expand our knowledge of normal development of the central nervous system (CNS) as well as help in deciphering the pathoge

Abutment

Myelin Molecules Limiting Nervous System Plasticity,of direction and trajectory (.). In contrast to the embryonic environment, the injured adult central nervous system (CNS) in mammals is overwhelmingly inhibitory for axon outgrowth, severely limiting nerve regeneration (.). The inability of axons to regrow after CNS injury has profound medical conse

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https://doi.org/10.1007/978-3-658-29589-9ori 1981) including cell/cell (Schnaar et al. 1998) and cell/extracellular matrix interactions (Cheresh et al. 1986). Three modes of action whereby gangliosides and their degradation products affect signal transduction have been proposed: (1) modulation of growth factor/hormone and integrin receptor

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Functional Role of Gangliosides in Neuronal Motility,euronal cell migration could expand our knowledge of normal development of the central nervous system (CNS) as well as help in deciphering the pathogenesis of various developmental dis orders (Aicardi 1994; Raymond et al. 1994; Uher and Golden 2000; Walsh and Goffinet 2000).