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Updating Stochastic Networks to Integrate Cross-Sectional and Longitudinal Studiesbuilding realistic trajectories from healthy patients to those with advanced disease. We focus on exploring whether we can ‘calibrate’ models learnt from these trajectories with real longitudinal data using Baum-Welch re-estimation.

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Risk-Reducing Surgery for Breast Cancer Patients with BRCA Mutationse inconsistent, but BPO seems to be associated with improved breast- and ovarian cancer‐specific mortality as well as improved all‐cause mortality among BRCA1/2 mutation carriers. Although prophylactic surgery does not address the cause of these cancers, which is the gene mutations, it is highly effective for cancer prevention and survival.

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