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Handbook of Experimental Pharmacology is approved in Europe to be given locoregionally as a therapy for sarcoma. TNF produced by the body mediates host responses in acute and chronic inflammatory conditions and aids in host protection from infection and malignancy. The biology of the TNF/TNF-receptor system was reviewed by ...

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Calcitonin gene-related peptides and their receptors,a region of potential amphipathic α-helix and a C-terminal amide. When coupled with the homology at the level of the primary structure, this allows significant cross-reactivity between these peptides and their cognate receptors [see 3 for review].

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