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Greener Methods for Amide Bond Synthesisst easily accomplished via condensation at high temperatures using amines and carboxylic acids, but peptide coupling agents are pervasively used to form amides under milder conditions. While these coupling agents are robust synthetic reagents, they are generally used in super stoichiometric amounts

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極肥胖

pacifist

dyspareunia

老巫婆

Direct C–H Functionalization Approaches to Pharmaceutically Relevant Molecules This is due to the prevalence of both aromatic moieties and heteroatoms in pharmaceutical, agrochemical, material, and natural products. More traditional and established cross-coupling approaches rely on tactically installed metal-activating groups, and as such, the transformation of these function

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