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Hypernatremia and hyponatremiantly develop during hospital stay [1–4]. They significantly contribute to hospital morbidity and mortality [1, 4–6]. The daily incidence and prevalence of hyponatremia (plasma [Na.] < 130 mmol/1) among hospital inpatients have been reported as 1% and 2.5% respectively, with approximately two thirds

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are involved in drug metabolism.Explores the role of receptoThis book presents various computer-aided drug discovery methods for the design and development of ligand and structure-based drug molecules. A wide variety of computational approaches are now being used in various stages of drug discovery

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Cost Models for Two-Dimensional Warrantiesby-two games in normal form (.) to sequential games. It is obvious that the analysis of conflict-solving strategies and metastrategies deals implicitly and some times explicitly with cooperation.. The emphasis on cooperation-promoting strategies plays therefore an important role within rational-choice analysis of two-actor problems.

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Combined Hydrodynamical and Empirical Modeling of Ocean Tides,representation of the real 1°-macroscopic nature of turbulent tidal currents. The quality of the representation was measured by the smoothness with which the hydrodynamically computed tidal field integrated thousands of empirical tide data uniformly over the world-wide oceans.

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