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https://doi.org/10.1007/978-3-662-43131-3ycobacterial bacille Calmette-Guerin (BCG) due to their capacity to colonize mucosal surfaces and invade macrophages in the liver, spleen and lymph nodes of the host.. Surface-display of the foreign antigens to be delivered, has in both these systems proven to be beneficial in eliciting an immune re

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https://doi.org/10.1007/978-3-662-65984-7sophisticated effective vaccines, thousands of people, mainly children, die each year as a result of vaccine-preventable diseases (Jordan Report 1995). A significant factor contributing to this mortality rate is the problem of implementing vaccination programs on a large scale due to the need for tr

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Mehr Energie durch Shaolin-Qi Gongeen implicated in severe infections in both human and animals, which are particularly severe for newborns and immunocompromised individuals. This microorganism has also been used as a model for the study of major histocompatibility complex (MHC) class I-restricted immune responses. Recent studies hi

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An Overview of Gram-Positive Bacteria as Vaccine Vehicles for Mucosal Immunization,s are urgently needed to cope with the problems associated with the distribution and administration of an increasing number of vaccines needed to prevent childhood diseases. It is predicted that by the year 2000 a cohort of approximately 125 million children in developing countries alone will need t

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Dendritic Cells as Targets for Mucosal Immunization,on is to capture, process and present antigens to unprimed T cells.. Dendritic cells are thus professional antigen presenting cells (APC) responsible for the generation of primary T cell responses. Members of this family are represented in most tissues, including the skin, the gut and the lungs, as

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