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Titlebook: Glycoprotein Hormones; Structure, Function, Joyce W. Lustbader,David Puett,Raymond W. Ruddon Conference proceedings 1994 Springer-Verlag Ne

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21#
發(fā)表于 2025-3-25 07:06:31 | 只看該作者
22#
發(fā)表于 2025-3-25 11:20:11 | 只看該作者
https://doi.org/10.1007/978-3-662-34530-6eptide hormone and a larger globular protein. As noted by Dyson and Wright (1), the active conformation of a small hormone or bioactive peptide may be imposed predominantly by the shape of the receptor, while regions of interest within a protein are inevitably involved in interactions within the mol
23#
發(fā)表于 2025-3-25 14:38:11 | 只看該作者
24#
發(fā)表于 2025-3-25 16:29:13 | 只看該作者
25#
發(fā)表于 2025-3-25 21:25:24 | 只看該作者
https://doi.org/10.1007/978-3-642-91188-0lt, uncombined α- and β-subunits, as well as α-β heterodimer, are secreted (1–3). Efficiency of α-β assembly in vitro, using purified urinary forms of the subunits, has also been reported to be low, with a kd of 0.6 μM (4).
26#
發(fā)表于 2025-3-26 01:34:36 | 只看該作者
27#
發(fā)表于 2025-3-26 07:49:14 | 只看該作者
28#
發(fā)表于 2025-3-26 10:57:36 | 只看該作者
https://doi.org/10.1007/978-3-642-91188-0lt, uncombined α- and β-subunits, as well as α-β heterodimer, are secreted (1–3). Efficiency of α-β assembly in vitro, using purified urinary forms of the subunits, has also been reported to be low, with a kd of 0.6 μM (4).
29#
發(fā)表于 2025-3-26 13:05:48 | 只看該作者
Where to from Here?however, the answers are apt to be biased by what you judge to be salable to a review committee. I think better answers come after the application has been submitted. This allows time to obtain data and make the goal salable at the next application three to five years later.
30#
發(fā)表于 2025-3-26 16:51:55 | 只看該作者
Folding of the β-Subunit of hCG and Its Role in Assembly of the α-β Heterodimerlt, uncombined α- and β-subunits, as well as α-β heterodimer, are secreted (1–3). Efficiency of α-β assembly in vitro, using purified urinary forms of the subunits, has also been reported to be low, with a kd of 0.6 μM (4).
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