Titlebook: Glutamate and Addiction; Barbara H. Herman,Jerry Frankenheim,Steven R. Zuki Book 2002 Springer Science+Business Media New York 2002 Opioid

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Glutamate Neurotransmission in the Course of Cocaine Addictionychostimulant dependence has been a major focus of investigation, especially following the cocaine epidemic of the 1980s. Despite early misconceptions that considered cocaine as a recreational drug devoid of abuse and addictive potential, the recent cocaine epidemic has revealed the harmful conseque

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Methamphetamine Toxicity, mood elevation, anorexia, increased mental alertness, enhanced physical endurance, and hyperthermia. The mood-elevating and positive-reinforcing effects most likely contribute to the high abuse liability of this drug. Indeed, MA abuse has increased across the United States at an alarming rate sinc

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Clinical Studies Using NMDA Receptor Antagonists in Cocaine and Opioid Dependenceamate, in laboratory models of alcohol and drug dependence .. As a result, we now have a wealth of information suggesting that glutamatergic neurotransmission is a major component of the neuroadaptive changes that mediate the development, maintenance, and expression of patterns of animal behavior th

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Ausblick auf künftige Entwicklungenr. Although clinical settings involving glutamate receptor modulators or antagonists usually involve stroke, acute brain injury, epilepsy, and neuropathic pain, both metabotropic and ionotropic classes of glutamate receptor also appear to play a role in addiction and cognition. For example, sensitiz