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Titlebook: Glucose-sensing Receptor in Pancreatic Beta-cells; Itaru Kojima Book 2018 Springer Nature Singapore Pte Ltd. 2018 Insulin secretion.Diabet

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發(fā)表于 2025-3-23 12:57:53 | 只看該作者
https://doi.org/10.1007/978-981-13-0002-8Insulin secretion; Diabetes; Sweet Taste Receptor; Glucoreceptor; Metabolism
12#
發(fā)表于 2025-3-23 14:54:16 | 只看該作者
KATP Channel-Independent Pathway and the Glucoreceptor,. Therefore, the first phase of glucose-induced secretion, i.e., fusion of the beta granule and the plasma membrane, likely arises from both glucose-receptor binding and closure of KATP channels. The molecular nature of the so-called KATP-independent glucose action appears to be diverse and still re
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發(fā)表于 2025-3-23 18:27:36 | 只看該作者
14#
發(fā)表于 2025-3-23 22:26:21 | 只看該作者
15#
發(fā)表于 2025-3-24 04:02:22 | 只看該作者
as identification, channel pathway, receptor signal and physiological role. Readers will gain a thorough understanding of the glucose-sensing receptor?and glucose metabolism in pancreatic beta-cells, new insights into the?pathophysiology of diabetes, and learn about new targets for the treatment of diabetes.?.978-981-13-0002-8
16#
發(fā)表于 2025-3-24 09:24:56 | 只看該作者
Book 2018iological role. Readers will gain a thorough understanding of the glucose-sensing receptor?and glucose metabolism in pancreatic beta-cells, new insights into the?pathophysiology of diabetes, and learn about new targets for the treatment of diabetes.?.
17#
發(fā)表于 2025-3-24 11:47:15 | 只看該作者
Learning Strategies and Learning Styles. Therefore, the first phase of glucose-induced secretion, i.e., fusion of the beta granule and the plasma membrane, likely arises from both glucose-receptor binding and closure of KATP channels. The molecular nature of the so-called KATP-independent glucose action appears to be diverse and still re
18#
發(fā)表于 2025-3-24 15:46:41 | 只看該作者
https://doi.org/10.1007/0-387-28310-2and PKC activity. Importantly, these rapid signals were independent of glucose metabolism and were reproduced by addition of nonmetabolizable glucose analogs. Since these signals were inhibited by inhibition of Gq or Gs, it is quite likely that glucose activates a cell-surface receptor and generates
19#
發(fā)表于 2025-3-24 22:47:14 | 只看該作者
https://doi.org/10.1007/978-1-4471-3089-5irst acts on the cell-surface glucose-sensing receptor and primes the metabolic pathway of glucose. Glucose then enters β-cells and is metabolized through already activated metabolic pathway. The receptor pathway and the metabolic pathway act coordinately to stimulate insulin secretion.
20#
發(fā)表于 2025-3-25 01:06:30 | 只看該作者
Book 2018 findings on the glucose-sensing receptor have now shed new light on the “glucoreceptor theory.”.This volume reviews recent advances concerning the glucose-sensing receptor in pancreatic beta-cells..The history of research into pancreatic beta-cells is long and complex; accordingly, the first chapte
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