Titlebook: Glial-Neuronal Signaling in Neuroendocrine Systems; Jeffrey G. Tasker,Jaideep S. Bains,Julie A. Chowen Book 2021 Springer Nature Switzerla

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https://doi.org/10.1007/978-3-322-92794-1eostasis and reproduction. While most circulating factors do not enter the brain because of the blood–brain barrier (BBB), homeostatic signals from the periphery converge on the hypothalamus—a brain region influencing feeding and energy expenditure—through a privileged route that bypasses the brain

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ation of the hypothalamic-pituitary-thyroid (HPT) axis, extend far beyond their role as barrier cells. This chapter summarizes the various mechanisms by which tanycytes contribute to the control of the HPT axis. These cells modulate thyroid hormone negative feedback regulation of hypophysiotropic th

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The Role of Microglia in the Developing Hypothalamusic hormones that serve to connect the nervous and endocrine systems. The organization and function of the discrete nuclei that comprise the hypothalamus have been well studied, yet the programs that govern their development remain poorly described. This paucity of understanding is especially true fo

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Fenestrated Capillary and Dynamic Neuro-Glial-Vascular Reorganization of the Adult Neurohypophysisation such as osmotic stimulation and lactation. Neurohypophysial glial cells, pituicytes engulf axon terminals and interpose between the axon terminals and fenestrated capillaries under healthy normal conditions, whereas chronic physiological stimulation increases the neuro-vascular contact area vi

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The Multifaceted Roles of Hypothalamic Astrocytes and Microglial Cells in Neuroendocrine and Autonomctions, metabolism and mood, among others. This complex function is achieved by the concerted action of neurons, astrocytes, and microglia within this nucleus. However, various pathophysiological conditions, particularly those involving a neuroinflammatory process, disturb the normal function and in

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Glia-Neuron Communication: Not a One-Way Streetof the hypothalamus, which is a key region of the brain responsible for maintaining energy balance. Specifically, energy excess primarily due to elevated levels of fats and lipids induces a neuroinflammatory response in the hypothalamus that impairs key regulatory mechanisms that maintain energy bal

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