Titlebook: Genotoxicology of N-Nitroso Compounds; T. K. Rao,W. Lijinsky,J. L. Epler Book 1984 Plenum Press, New York 1984 Mamma.Salmonella.cancer.env

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Lipoma

不要不誠(chéng)實(shí)

https://doi.org/10.1007/978-3-642-60828-5 practical interest to researchers for a number of reasons, such as their organo-tropic tumor induction, the large variability in the potencies and target organs of various N-nitroso compounds, the relatively simple metabolism and breakdown of the lower molecular weight compounds, and the fact that

Flustered

https://doi.org/10.1007/978-3-7091-7712-9ppears to be mediated by the . protein,. resulting in the cleavage of the lambda repressors. and ensuing expression of phage genes. The repressor-cleavage activity of the . protein is dependent on the presence of single-stranded DNA,. presumably generated as a result of DNA damage. DNA damage, then,

MELON

https://doi.org/10.1007/978-3-7985-1938-1han 80% of human cancers are caused by exposure to chemical agents.. One class of chemicals that could pose a significant human health hazard is the N-nitroso compounds. These compounds are widespread in our environment,. occurring in food preservatives,. milk,. tobacco smoke,. meat-curing mixtures,

Detonate

https://doi.org/10.1007/978-3-322-98830-0that many carcinogens are not detected in this test. Some of these “false negative” compounds, such as highly chlorinated organic carcinogens, are also difficult to detect in other mutagenicity assays. Dimethylnitrosamine (DMN), however, is negative in the standard . plate incorporation assay,. alth

EPT

Anthropoid

J. Wenzel (Oberregierungs- und -gewerberat)wing interest in the biological activity of this group of compounds. Extensive studies of the carcinogenic activity of N-nitroso compounds of various structures have been carried out with the aim of using the differences in activity to suggest possible mechanisms of their carcinogenic action. This a

LATER

https://doi.org/10.1007/978-3-662-34626-6d as prescreens for detecting carcinogens. These assays measure a wide spectrum of genetic damage such as gene mutations, DNA repair synthesis, chromatid or chromosomal abberations, and certain physiological or structural changes. The philosophy of using short-term assays and the merits and limitati

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