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Titlebook: Genotoxicity and DNA Repair; A Practical Approach L. María Sierra,Isabel Gaiv?o Book 2014 Springer Science+Business Media New York 2014 DNA

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https://doi.org/10.1007/978-3-642-91799-8phila are in vivo short-term assays that assess genetic damage induction in somatic cells of adult flies after larval exposure. They are less onerous than other Drosophila tests (the germinal ones) and are very sensitive, specific, and accurate. All of them are based in obtaining heterozygous offspr
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https://doi.org/10.1007/978-3-662-29093-4in vitro approaches, neglecting the repair and metabolic properties of the whole organism, some doubts about the accuracy of the obtained results exist. To overcome this gap more in vivo approaches testing the potential genotoxic risk of nanomaterials are required. In this context we propose to use
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https://doi.org/10.1007/978-3-662-29092-7cer. It is important to have methods available to test chemicals to which humans may be exposed for their mutagenic potential. In 2011 the Organization for Economic Cooperation and Development adopted a test guideline on the use of transgenic rodent (TGR) assays for investigating the mutagenic poten
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978-1-4939-4829-1Springer Science+Business Media New York 2014
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