| 書目名稱 | Genomic Imprinting |
| 副標(biāo)題 | Methods and Protocol |
| 編輯 | Andrew Ward |
| 視頻video | http://file.papertrans.cn/383/382897/382897.mp4 |
| 概述 | Includes supplementary material: |
| 叢書名稱 | Methods in Molecular Biology |
| 圖書封面 |  |
| 描述 | Genomic imprinting is the process by which gene activity is regulated according to parent of origin. Usually, this means that either the maternally inherited or the paternally inherited allele of a gene is expressed while the opposite allele is repressed. The phenomenon is largely restricted to mammals and flowering plants and was first recognized at the level of whole genomes. Nuclear transplantation experiments carried out in mice in the late 1970s established the non-equivalence of the maternal and paternal genomes in mammals, and a similar conclusion was drawn from studies of interploidy crosses of flowering plants that extend back to at least the 1930s. Further mouse genetic studies, involving animals carrying balanced translocations (reviewed in Chapter 3), indicated that imprinted genes were likely to be widely scattered and would form a minority within the mammalian genome. The first imprinted genes were identified in the early 1990s; over forty are now known in mammals and the list continues steadily to expand. |
| 出版日期 | Book 2002 |
| 版次 | 1 |
| doi | https://doi.org/10.1385/1592592112 |
| isbn_softcover | 978-1-61737-164-6 |
| isbn_ebook | 978-1-59259-211-1Series ISSN 1064-3745 Series E-ISSN 1940-6029 |
| issn_series | 1064-3745 |
| copyright | Humana Press 2002 |
|Archiver|手機(jī)版|小黑屋|
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