Titlebook: Genomic Applications in Pathology; George Jabboure Netto,Iris Schrijver Book 20151st edition Springer Science+Business Media New York 2015

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Piyush Tiwari,Jyoti Rao,Jennifer Daye testing, let alone genomic analysis. Pathologists, given their background in molecular diagnostics and experience directing clinical laboratories, must play a major role in translating genomic technology to patient care. This chapter reviews the significant progress that the pathology community ha

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Wang-Taek Jun,Renee Prendergastuction of novel diagnostic tests. Opponents argue that patents are unnecessary for discovery, and that they raise costs, decrease patient access, and harm innovation in the field of molecular pathology. In two recent Supreme Court cases, . and ., the Court ruled that biological correlations and huma

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Service Policy and Development,ings essential for the use of novel classes of targeting therapies. Although there is considerable enthusiasm for the use of the discoveries of cancer genomics for personalized medicine in clinical practice, the number of new classes of biomarkers incorporated into cancer diagnosis and treatment rem

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https://doi.org/10.1007/978-3-030-91131-7xpensive to perform analysis on more than a few exons or genes at a time. The nature of high-throughput sequencing has altered these calculations, and large panels of potentially pathogenic genes or even whole exomes or genomes are sequenced routinely. However, the techniques and equipment useful fo

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Drawing the Evaluation Together,lel sequencing technologies. NGS has dramatically expanded the capabilities of laboratories by multiplexing and streamlining DNA sequencing workflows. Replacing traditional target amplification techniques with in-solution enrichment technologies has simplified sequencing template preparation, greatl